In a July 16 TED talk, we’ll present an overview of our new sample preparation kit developed to isolate RNA from FFPE tissue samples. This product is designed to support the Advanta™ IO Gene Expression Assay workflow. We’ll introduce the Advanta FFPE RNA Extraction Kit, provide kit positioning and discuss available sales tools.
Afterward, we’ll provide an update on our Imaging Mass Cytometry™ User Group Meeting in Seattle.
Register for one of the two TED sessions:
Monday, July 16, 8:00–9:00 am PT
Monday, July 16, 5:00–6:00 pm PT
Fluidigm Joins Euro–BioImaging Industry Board
Outreach efforts include raising awareness of Imaging Mass Cytometry across Europe
Fluidigm recently joined the Euro-BioImaging (EuBI) Industry Board to help increase awareness of our technology across multiple sites in Europe. Our Gold-level membership afforded team members the chance to present Imaging Mass Cytometry™ to the board and will assist with outreach to EuBI members about potential training seminars, educational webinars and other promotional activities.
The platform provides open access to a range of state-of-the-art technologies in biological and biomedical imaging for life science researchers. In addition, EuBI offers image data support and training for infrastructure users and providers. The EuBI consists of 29 specialized imaging facilities granting access to scientists from Europe and beyond.
Tell customers and prospects they can learn more about how to benefit from our board membership with Imaging Mass Cytometry technology at the EuBl website.
Event | flowcytometryUK 2018
Invite customers to attend our Fluidigm workshop at the July 18–20 meeting in Edinburgh
At a workshop hosted by Fluidigm at the flowcytometryUK meeting in Edinburgh, Scotland on July 18, one of our Cambridge University customers will share new discoveries made using mass cytometry and present his work on the role of the immune system in human pregnancy. Uterine mucosa (termed the decidua) is highly populated with natural killer cells during pregnancy. The researcher’s goal is to understand the role these cells play both in normal term births and in failed pregnancies. He has used Helios™ to characterize the cells and found them to be distinct from their peripheral blood counterparts in matched donors. He plans to further characterize the distribution of these cells throughout the maternal-fetal interface using the Hyperion™ Imaging System.
In a talk supporting this presentation, the Fluidigm Field Application Specialist team will give an introduction to mass cytometry and Imaging Mass Cytometry™.
Download the Helios flowcytometryUK Meeting 2018 flyer to share with customers in the EU. Customers can also find more program details at the flowcytometryUK website.
Mass cytometry is helping scientists unravel the complex CD4 T cell populations involved in HIV. AIDS researcher Benoit Favier of CEA-Université Paris Sud and colleagues at several other institutions in France have clarified a controversy about the usefulness of a specific protein called CD32a as a biomarker for HIV-infected CD4 T cells. As part of the ANRS CO6 PRIMO Cohort clinical trial, the group used a 35-marker mass cytometry panel to analyze PBMC from cohort participants in early-stage HIV infection before and after effective combination retroviral therapy (cART).
The researchers required high-dimensional analysis because standard flow cytometry approaches could not capture the full diversity of the CD4 T cell compartment in a single experiment, which led to conflicting data reported in the literature. The group used mass cytometry to expand its panel to include both typical and atypical T cell markers, along with multiple CD32a/b clones reactive to specific protein variants. Doing so provided a clear picture of biomarker expression before, during and after cART; and in normal subjects.
As the authors noted in the publication, “High-dimensional analyses are critical for disentangling the numerous cellular and molecular events induced by HIV infection.” The investigators concluded that the role of CD32+ CD4 T cells should be re-evaluated with regard to their role in HIV persistence and reservoirs.
Share this Frontiers in Immunology paper with customers curious about the value that high-dimensional mass cytometry analysis can bring to their work, since biomarker discovery is a key application for any clinical researcher studying disease.
